Born in Giuliano di Roma, small town in the province of Frosinone, into a wealthy family, she was given the name Constance. Left motherless at the age of six years was educated at the Conservatory of the Nuns of Charity of St. Clare of Ferentino. Here the couple's religious vocation and the 16 December 1830 took vows as a nun with the name of Mary Catherine of St. Rose of Viterbo in the same institution, becoming secretary.
From 1842 to the 1858 camerlenga was the Abbess Maria Aloisia Castles.
In 1859, together with the superior Castles and three other sisters, part to Cairo to open a new monastery of the congregation. Shortly after his arrival, however, Castelli mother falls ill and responsibility of the works of the new house fell on Catherine, accordance with the provisions of the Apostolic Delegate, Archbishop. Vujcic, who also wrote a new regulation for the community .
In 1863 Catherine was elected superior of the Community , which was then canonically established in 1868 with the name of the Franciscan Tertiary Cairo (from 1950 take the name of the Franciscan Missionary Sisters of the Immaculate Heart of Mary).
During the years when Caterina Troiani guide the Community arrives in Egypt to open seven new homes for the care and education of abandoned children.
Catherine is the Mother Superior General until his death. The procedures for his cause for canonization were initiated in 1944. It’ She was beatified by Pope John Paul II 14 aprile del 1985.
His memory is celebrated on 6 May.